Anti-HP Polyclonal Antibody
产品名称: Anti-HP Polyclonal Antibody
英文名称: Anti-HP Polyclonal Antibody
产品编号: K002841P
产品价格: null
产品产地: 北京
品牌商标: Solarbio
更新时间: 2025-01-14T09:56:36
使用范围:
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
- 电话 : 178****1073 点击查看
- 传真 : 点击查看
- 邮箱 : 3193328036@qq.com
- 二维码 : 点击查看
Anti-HP Polyclonal Antibody
Anti-HP Polyclonal Antibody
品牌:solarbio | 货号:K002841P
英文名称 | Anti-HP Polyclonal Antibody |
---|---|
别名 | BP;HP2ALPHA2;HPA1S |
应用 | WB IHC |
稀释比例 | WB 1:500-2000. IHC 1:50-200. |
交叉反应 | Human Mouse Rat |
蛋白分子量 | 45kDa |
Gene ID | 3240 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG |
免疫原 | Recombinant protein of human HP |
性状 | 液体 |
Public Immunogen Range | Recombinant protein of human HP |
Subcellular Locations | Secreted |
Swiss Prot | P00738 |
克隆类型 | Polyclonal Antibody |
背景资料 | This gene encodes a preproprotein, which is processed to yield both alpha and beta chains, which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin, which allows degradative enzymes to gain access to the hemoglobin, while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy, the incidence of coronary artery disease in type 1 diabetes, Crohn's disease, inflammatory disease behavior, primary sclerosing cholangitis, susceptibility to idiopathic Parkinson's disease, and a reduced incidence of Plasmodium falciparum malaria. The protein encoded also exhibits antimicrobial activity against bacteria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. |