Anti-CDC42 Polyclonal Antibody
产品名称: Anti-CDC42 Polyclonal Antibody
英文名称: Anti-CDC42 Polyclonal Antibody
产品编号: K002379P
产品价格: null
产品产地: 北京
品牌商标: Solarbio
更新时间: 2025-01-13T13:42:34
使用范围:
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
- 电话 : 178****1073 点击查看
- 传真 : 点击查看
- 邮箱 : 3193328036@qq.com
- 二维码 : 点击查看
Anti-CDC42 Polyclonal Antibody
Anti-CDC42 Polyclonal Antibody
品牌:solarbio | 货号:K002379P
英文名称 | Anti-CDC42 Polyclonal Antibody |
---|---|
别名 | CDC42Hs;G25K;TKS |
应用 | WB IHC |
稀释比例 | WB 1:500-2000. IHC 1:50-200. |
交叉反应 | Human Mouse |
蛋白分子量 | 21kDa |
Gene ID | 998 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG |
免疫原 | Recombinant protein of human CDC42 |
性状 | 液体 |
Public Immunogen Range | Recombinant protein of human CDC42 |
Subcellular Locations | Cell membrane Cytoplasm Cytoplasmic side Lipid-anchor Midbody centrosome cytoskeleton microtubule organizing center spindle |
Swiss Prot | P60953 |
克隆类型 | Polyclonal Antibody |
背景资料 | The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20. |