CRLF2 Polyclonal Antibody
产品名称: CRLF2 Polyclonal Antibody
英文名称: CRLF2 Polyclonal Antibody
产品编号: K001865P
产品价格: null
产品产地: 北京市通州区马驹桥联
品牌商标: solarbio
更新时间: 2025-01-13T13:42:34
使用范围:
北京索莱宝科技有限公司
- 联系人 : 索莱宝-龚思雨
- 地址 : 北京市通州区中关村科技园区通州园金桥科技产业基地景盛南四街15号85A三层
- 邮编 : 101102
- 所在区域 : 北京
- 电话 : 178****1073 点击查看
- 传真 : 点击查看
- 邮箱 : 3193328036@qq.com
- 二维码 : 点击查看
Anti-CRLF2 Polyclonal Antibody
品牌:solarbio | 货号:K001865P
英文名称 | Anti-CRLF2 Polyclonal Antibody |
---|---|
别名 | CRL2;CRLF2Y;TSLPR |
应用 | WB |
稀释比例 | WB 1:200-1000. |
交叉反应 | Human Mouse Rat |
蛋白分子量 | 42kDa |
Gene ID | 64109 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
纯化方法 | Affinity purification |
亚型 | IgG |
免疫原 | Recombinant protein of human CRLF2 |
性状 | 液体 |
Public Immunogen Range | Recombinant protein of human CRLF2 |
Subcellular Locations | Cell membrane Secreted Single-pass type I membrane protein |
Swiss Prot | Q9HC73 |
克隆类型 | Polyclonal Antibody |
背景资料 | This gene encodes a member of the type I cytokine receptor family. The encoded protein is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Rearrangement of this gene with immunoglobulin heavy chain gene (IGH) on chromosome 14, or with P2Y purinoceptor 8 gene (P2RY8) on the same X or Y chromosomes is associated with B-progenitor acute lymphoblastic leukemia (ALL) and Down syndrome ALL. Alternatively spliced transcript variants have been found for this gene. |