PARK7 polyclonal antibody
产品名称： PARK7 polyclonal antibody
英文名称： PARK7 polyclonal antibody
产品编号： PAB12799
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against recombinant PARK7.
- Immunogen:
- Recombinant His fusion protein corresponding to human PARK7.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Purification:
- Affinity purification
- Concentration:
- 1 mg/mL
- Storage Buffer:
- In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:2000-1:5000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Linking DJ-1 to neurodegeneration offers novel insights for understanding the pathogenesis of Parkinson's disease.
Bonifati V, Oostra BA, Heutink P.J Mol Med. 2004 Mar;82(3):163-74. Epub 2004 Jan 8.
- 2.
- Crystal structure of human DJ-1, a protein associated with early onset Parkinson's disease.
Tao X, Tong L.J Biol Chem. 2003 Aug 15;278(33):31372-9. Epub 2003 May 21.
- 3.
- Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism.
Bonifati V, Rizzu P, van Baren MJ, Schaap O, Breedveld GJ, Krieger E, Dekker MC, Squitieri F, Ibanez P, Joosse M, van Dongen JW, Vanacore N, van Swieten JC, Brice A, Meco G, van Duijn CM, Oostra BA, Heutink P.Science. 2003 Jan 10;299(5604):256-9. Epub 2002 Nov 21.
- Entrez GeneID:
- 11315
- Gene Name:
- PARK7
- Gene Alias:
- DJ-1,DJ1,FLJ27376,FLJ34360,FLJ92274
- Gene Description:
- Parkinson disease (autosomal recessive, early onset) 7
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq
- Other Designations:
- OTTHUMP00000001348,OTTHUMP00000001349,OTTHUMP00000001350,OTTHUMP00000001351,Parkinson disease protein 7,oncogene DJ1,protein DJ-1
- Gene Pathway