Anti-DSC2 Polyclonal Antibody

商品货号：	商品品牌：	规格	基本售价：	选择规格
K001886P-50ul	solarbio	50ul	960.00元
K001886P-100ul	solarbio	100ul	1600.00元

英文名称	Anti-DSC2 Polyclonal Antibody
别名	ARVD11;CDHF2;DG2;DGII/III;DSC3
应用	WB IHC
稀释比例	WB 1:500-2000. IHC 1:50-200.
交叉反应	Human
蛋白分子量	100kDa
Gene ID	1824
保存	Store at -20°C. Avoid freeze / thaw cycles.
储存液	Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法	Affinity purification
亚型	IgG
免疫原	Recombinant protein of human DSC2
性状	液体
Public Immunogen Range	Recombinant protein of human DSC2
Subcellular Locations	Cell junction Cell membrane Single-pass type I membrane protein desmosome
Swiss Prot	Q02487
克隆类型	Polyclonal Antibody
背景资料	This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants.