DPABH-01374 detects endogenous levels of PDLIM5 only when phosphorylated at Tyr251.May play an important role in the heart development by scaffolding PKC to the Z-disk region. May play a role in the regulation of cardiomyocyte expansion. Overexpression promotes the development of heart hypertrophy. Contributes to the regulation of dendritic spine morphogenesis in neurons. May restrain postsynaptic growth of excitatory synapses.Shipped at 4°C. Store at -20oC. *   http://www.creative-diagnostics.com/Anti-PDLIM5-PAb-199508-489.htm