EGR2 polyclonal antibody
产品名称: EGR2 polyclonal antibody
英文名称: EGR2 polyclonal antibody
产品编号: PAB7314
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of EGR2.
- Immunogen:
- A synthetic peptide corresponding to human EGR2.
- Sequence:
- HGTAGPDRKPFPC
- Host:
- Goat
- Theoretical MW (kDa):
- 50.3
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- ELISA (1:64000)
Western blot (0.03-0.1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3-5 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Neuropathy-associated Egr2 mutants disrupt cooperative activation of myelin protein zero by Egr2 and Sox10.
LeBlanc SE, Ward RM, Svaren J.Mol Cell Biol. 2007 May;27(9):3521-9. Epub 2007 Feb 26.
- Applications
- Western Blot (Cell lysate)
- EGR2 polyclonal antibody (Cat # PAB7314) (0.03 ug/mL) staining of HepG2 cell lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
- Entrez GeneID:
- 1959
- Protein Accession#:
- NP_00.0390.2
- Gene Name:
- EGR2
- Gene Alias:
- AT591,CMT1D,CMT4E,DKFZp686J1957,FLJ14547,KROX20
- Gene Description:
- early growth response 2 (Krox-20 homolog, Drosophila)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- KROX-20, Drosophila, homolog (early growth response-2),Krox-20 homolog,OTTHUMP00000062133,early growth response 2 protein
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Cardiovascular Diseases
- Charcot-Marie-Tooth Disease
- Deafness
- Deafness
- Diabetes Complications
- Genetic Predisposition to Disease
- Hereditary Central Nervous System Demyelinating Diseases
- Lupus Erythematosus, Systemic
- Metabolic Syndrome X
- Neoplasms
- Osteoporosis
- Ovarian Neoplasms
- Schizophrenia
- Scoliosis