CTLA4 monoclonal antibody, clone AS32
产品名称: CTLA4 monoclonal antibody, clone AS32
英文名称: CTLA4 monoclonal antibody, clone AS32
产品编号: MAB1848
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant CTLA4.
- Immunogen:
- Recombinant protein corresponding to extracellular region of human CTLA4.
- Host:
- Mouse
- Reactivity:
- Human
- Specificity:
- This antibody recognizes the extra-cellular domain of human CD152 (also called CTLA-4).
- Form:
- Liquid
- Isotype:
- IgG1
- Storage Buffer:
- In PBS (0.08% sodium azide)
- Storage Instruction:
- Store at 4°C. Do not freeze.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Application Image
- Inhibition Assay
- Entrez GeneID:
- 1493
- Gene Name:
- CTLA4
- Gene Alias:
- CD152,CELIAC3,CTLA-4,GSE,IDDM12
- Gene Description:
- cytotoxic T-lymphocyte-associated protein 4
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq
- Other Designations:
- OTTHUMP00000163781,cytotoxic T-lymphocyte-associated antigen 4,cytotoxic T-lymphocyte-associated serine esterase-4,ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
- Interactome
- Related Disease
- Abortion, Habitual
- Abortion, Spontaneous
- Abruptio Placentae
- Acquired Immunodeficiency Syndrome
- Acute Disease
- Addison Disease
- Adenocarcinoma
- Adenoma
- Alcoholism
- Alopecia Areata
- Anemia, Aplastic
- Anemia, Hemolytic, Autoimmune
- Arthritis, Juvenile Rheumatoid
- Arthritis, Psoriatic
- Arthritis, Rheumatoid
- Asthma
- Asthma
- Atherosclerosis
- Autoimmune Diseases